Oral microbial flora consist of numerous bacterial taxa, ranging from aerob
es through fastidious anaerobes, and fungi, viruses, and protozoa. Many of
these bacteria are unique to the oral cavity. The organisms exist in a comp
lex interrelationship that is regulated and maintained by physical and meta
bolic microbial interactions, and by environmental factors, such as saliva
and diet. Many of these organisms are relatively harmless, although others
are significant pathogens, producing local and systemic diseases in healthy
and compromised individuals.