Sw. Fosko et al., BASAL-CELL CARCINOMA INVOLVING THE LACRIMAL CANALICULUS - A DOCUMENTED MECHANISM OF TUMOR SPREAD, Dermatologic surgery, 23(3), 1997, pp. 203-206
BACKGROUND. Basal cell carcinoma (BCC) is the most common malignant tu
mor of the eyelid and periocular tissues but rarely involves the lacri
mal system. In addition, BCC in this location frequently recur due to
inadequate margin control. A further understanding of the pathophysiol
ogy of periocular BCC was addressed. OBJECTIVE. To report two rare cas
es of BCC involving the lacrimal system and to account for subtle clin
ical features yet extensive tissue spread of periocular BCC. METHODS.
Using the Mohs micrographic surgical technique, we describe two patien
ts with a BCC involving the lacrimal system that histologically tracke
d beyond clinically apparent margins. RESULTS. Spread of BCC along muc
osal surfaces is documented. CONCLUSION. Rare involvement of the lacri
mal system by a BCC is reported in two patients. Superficial histologi
c involvement can explain the ability of BCC to extend locally and esc
ape adequate treatment. (C) 1997 by the American Society for Dermatolo
gic Surgery, Inc.