Effect of ENDUROX (TM) on metabolic responses to submaximal exercise

Claims that ENDUROX(TM) enhances performance by altering metabolic response s to exercise were tested. In a double-blind crossover design, 10 male subj ects were randomly assigned to consume 400 mg of placebo or 800 mg ENDUROX( TM) for 7 days. Cycle ergometry was performed for 30 minutes at 25%, follow ed by 10 min at 65% of peak oxygen consumption. After a 1-week washout peri od, subjects performed the identical exercise protocol following 7 days of reciprocal supplemental conditions. Expired gases were collected and analyz ed continuously for oxygen consumption, minute ventilation, and respiratory exchange ratio. Heart rate, blood pressure, rating of perceived exertion, blood lactate, and serum glycerol data were also collected at regular inter vals. A two-way ANOVA with repeated measures revealed no significant main o r interaction effects involving group differences (p > 0.05) between trials for any variable during rest, 25% or 65% (VO2 peak), or recovery. Our find ings do not support the ergogenic claims for ENDUROX(TM).