Isolation and structure elucidation of new salfredin-type metabolites fromCrucibulum laeve DSM 1653 and DSM 8519

Authors
Neumann, T Schlegel, B Hoffmann, P Heinze, S Grafe, U
Citation
T. Neumann et al., Isolation and structure elucidation of new salfredin-type metabolites fromCrucibulum laeve DSM 1653 and DSM 8519, J BASIC MIC, 39(5-6), 1999, pp. 357-363
Citations number
5
Categorie Soggetti
Microbiology
Journal title
JOURNAL OF BASIC MICROBIOLOGY
ISSN journal
0233111X → ACNP
Volume
39
Issue
5-6
Year of publication
1999
Pages
357 - 363
Database
ISI
SICI code
0233-111X(1999)39:5-6<357:IASEON>2.0.ZU;2-E
Abstract
New salfredin-type chromene and benzofurane metabolites (4-7) were isolated from submerged cultures of the fungal strains Crucibulum laeve DSM 1653 an d C. laeve DSM 8519. The structures were elucidated on the basis of UV-VIS spectroscopic, mass spectrometric and NMR spectroscopic evidence. The new m etabolites are discussed as intermediates and shunt metabolites of the fung al aromatic pathway leading to A-, B- and C-type salfredins.