LIGATIONAL BEHAVIOR OF FLUOROIMINES TOWARDS ORGANOBORON(III) AND POTENTIATION OF THEIR MICROBIOCIDAL ACTIVITY

Complexes of fluoroimines (prepared by the condensation of 2-fluoroben zaldehyde and 1-(2-fluorophenyl) ethanone with hydrazinecarboxamide or hydrazinecarbothioamide) with organoboron(lll) were synthesized and c haracterized by elemental analyses, conductivity measurements, molecul ar weight determinations and spectroscopic techniques. It has been con cluded that preferential binding of the chelating ligands is anionic b identate, coordinating with the central boron atom through oxygen of c arbonyl group or sulfur of thionyl group and azomethine nitrogen. The complexes, PhB(OH)((FNX)-N-n), PhB((FNX)-N-n)(2) and their parent fluo roimines have been screened in vitro against a number of microbes and it is seen that the coordination of boron atom had pronounced effect o n the microbiocidal activity of the ligands.