R. Caldara et al., Effects of pancreas transplantation on late complications of diabetes and metabolic effects of pancreas and islet transplantation, J PED END M, 12, 1999, pp. 777-787
Pancreas transplantation has become an accepted therapeutic approach to tre
at insulin-dependent diabetes mellitus, successfully restoring normoglycemi
a. In contrast, islet transplantation is still in the experimental phase, o
nly a few operations having being performed worldwide. The aim of this revi
ew is to analyze the effects of pancreas transplantation on the late compli
cations of diabetes and to report the endocrine-metabolic effects of pancre
as and isles transplantation.