Thermodynamics of enzyme-catalyzed reactions: Part 6 - 1999 update

This review serves to update previously published evaluations of equilibriu m constants and enthalpy changes for enzyme-catalyzed reactions. For each r eaction the following information is given: the reference for the data; the reaction studied; the name of the enzyme used and its Enzyme Commission nu mber; the method of measurement; the conditions of measurement [temperature , pH, ionic strength, and the buffer(s) and cofactor(s) used]; the data and an evaluation of it; and, sometimes, commentary on the data and on any cor rections which have been applied to it or any calculations for which the da ta have been used. The data from 96 references have been examined and evalu ated. Chemical Abstract Service registry numbers are given for the substanc es involved in these various reactions. There is also a cross reference bet ween the substances and the Enzyme Commission numbers of the enzymes used t o catalyze the reactions in which the substances participate. (C) 1999 Amer ican Institute of Physics and American Chemical Society. [S0047-2689(99)002 04-4].