A CASE OF ANGIOSARCOMA OF THE BREAST

This is a case report of a 20-year-old woman who had primary angiosarc oma of the left breast, with metastases to the spleen and ovary, Eight months after detecting a mass in her breast, she underwent mastectomy with biopsy of the ipsilateral axillary lymph nodes, splenectomy and bilateral oophorectomy, Five months after the operation, the patient s uccumbed to lung metastases. Angiosarcoma of the breast is a rare cond ition with a poor prognosis, and there are no established chemotherape utic regimens as yet. Immunohistochemical staining for endoglin, known to be expressed mainly on the surface of endothelial cells, was posit ive. This suggests the possibility of treating angiosarcoma with anti- endoglin monoclonal antibodies.