CD56+lymphoma presenting as a testicular tumor

Citation
G. Guler et al., CD56+lymphoma presenting as a testicular tumor, LEUK LYMPH, 36(1-2), 1999, pp. 207
Citations number
11
Categorie Soggetti
Hematology,"Onconogenesis & Cancer Research
Journal title
LEUKEMIA & LYMPHOMA
ISSN journal
10428194 → ACNP
Volume
36
Issue
1-2
Year of publication
1999
Database
ISI
SICI code
1042-8194(199912)36:1-2<207:CPAATT>2.0.ZU;2-U
Abstract
A case of an unusual lymphoma type, CD56 (+) T/NK lymphoma, presenting as a testicular tumor is described. A 35 year old man who presented with right testicular swelling, underwent right inguinal orchiectomy, with a presumpti ve diagnosis of abscess or malignancy. Histopathology showed a diffuse mixe d large and small cell lymphoma with a focal angiocentric growth pattern. I munohistochemically CD45RO and CD56 were found to be positive in the neopla stic cells. Insitu hybridization assay for EBV showed the presence of EBV r elated small ribonucleic acid sequences (EBER) within the tumor cells. Desp ite systemic chemotherapy, the patient had an aggressive clinical course wi th two skin and left testicular recurrences in the first year of his diseas e.