Inflammation is considered to be a leading cause of morbidity in systemic l
upus erythematosus (SLE), yet inflammatory periodontal involvement is rarel
y encountered. A young lady suffering from active SLE accompanied by severe
periodontal loss, manifested by gingival recession of all her teeth, was r
eferred to our clinic for treatment. The association between periodontal in
volvement and connective tissue diseases is unclear, and the literature dea
ling with periodontal involvement in patients suffering from Sjogren's synd
rome and rheumatoid arthritis is comprised of studies showing both normal a
nd pathological periodontal status. We discuss the possible underlying mech
anisms.