A. Guiet-bara et al., Magnesium pidolate and magnesium aspartate effects on human amniotic membrane ionic permeability in vitro, MAGNES RES, 12(4), 1999, pp. 251-256
The effects of Mg pidolate and Mg aspartate were studied on the ionic trans
fer through a membraneous model: the human isolated amniotic membrane. The
ionic transfer was evaluated by the measure of the total conductance in the
maternal to fetal way (GtM) Emd in the fetal to maternal way (GtF) and of
the ionic fluxes (F1 on the maternal side (MS), F2 on the fetal side (FS))
and of the ratio F1/F2. Whatever the Mg pidolate concentration, GtM and GtF
remained constant. Mg aspartate had a concentration-dependent effect on Gt
M (decrease-increase) and a monophasic effect on GtF (decrease). F1 and F2
were decreased by the two Mg salts, and the ratio F1/F2 remained constant a
fter addition of Mg pidolate and was increased by Mg aspartate. The results
were explained in terms of screening and/or binding interactions with the
polar surface moieties and were compared with results obtained in previous
studies with other Mg salts. The results indicated the importance of the an
ion associated with Mg element in the ionic transfer.