No evidence of hypoxic tissue on F-18-fluoromisonidazole PET after intracerebral hemorrhage

Authors
Hirano, T Read, SJ Abbott, DF Sachinidis, JI Tochon-Danguy, HJ Egan, GF Bladin, CF Scott, AM McKay, WJ Donnan, GA
Citation
T. Hirano et al., No evidence of hypoxic tissue on F-18-fluoromisonidazole PET after intracerebral hemorrhage, NEUROLOGY, 53(9), 1999, pp. 2179-2182
Citations number
13
Categorie Soggetti
Neurology,"Neurosciences & Behavoir
Journal title
NEUROLOGY
ISSN journal
00283878 → ACNP
Volume
53
Issue
9
Year of publication
1999
Pages
2179 - 2182
Database
ISI
SICI code
0028-3878(199912)53:9<2179:NEOHTO>2.0.ZU;2-Q
Abstract
We studied six patients after intracerebral hemorrhage (ICH) and eight cont rols using positron emission tomography (PET) with to determine whether a z one of tissue hypoxia, possibly representing "penumbral" tissue, exists sur rounding an intracerebral hemorrhage. None of the stroke patients, studied 24 to 43 hours after symptom onset, nor any of the controls exhibited areas of tissue hypoxia on F-18-fluoromisonidazole PET images. These findings ma y have implications for the treatment of intracerebral hemorrhage with neur oprotective strategies.