Screening of Korean plants against human immunodeficiency virus type 1 protease

Authors
Min, BS Bae, KH Kim, YH Miyashiro, H Hattori, M Shimotohno, K
Citation
Bs. Min et al., Screening of Korean plants against human immunodeficiency virus type 1 protease, PHYTOTHER R, 13(8), 1999, pp. 680-682
Citations number
7
Categorie Soggetti
Pharmacology & Toxicology
Journal title
PHYTOTHERAPY RESEARCH
ISSN journal
0951418X → ACNP
Volume
13
Issue
8
Year of publication
1999
Pages
680 - 682
Database
ISI
SICI code
0951-418X(199912)13:8<680:SOKPAH>2.0.ZU;2-X
Abstract
With the aim of finding novel anti-human immunodeficiency virus agents from natural products, 93 MeOH extracts of Korean plants were screened for thei r inhibitory activities against HIV-1 protease, The most potent inhibition was shown by the root of Rodiola rosea with 70.4% inhibition at a concentra tion of 100 mu g/mL. Copyright (C) 1999 John Whey & Sons, Ltd.