Epidemiological studies have shown a higher incidence of multiple scle
rosis (MS) in regions with higher intake of fat mainly of animal origi
n. Double blind studies on the effect of dietary supplementation with
essential fatty acids (EFS) reveal trends towards a lower relapse rate
and progression speed but fail statistical significance, One long ter
m uncontrolled fat restriction study indicated fewer relapses and slow
er progression. Therefore if should be evaluated, whether an adjuvant
therapy of EFS-supplementation and restriction of saturated fatty acid
s enhances the effect of immunomodulators (e. g. Interferon-beta or Co
polymer-1).