Acceptance of prenatal diagnosis and termination of pregnancy in the case o
f an affected fetus may vary from one country to another, depending on the
health system,religious belief, cultural and educational backgrounds of the
population. Following a previous study on couples at risk for a haemoglobi
n disorder in Lebanon, we have here interviewed 90 couples at risk for a va
riety of genetic disorders, in order to assess their acceptance of prenatal
diagnosis and the variables that might influence their choice. Overall, 54
per cent of couples said they would request diagnosis in their next pregna
ncy, while 26 per cent were opposed to such a:procedure. In 87.5 per cent o
f cases, the reason for refusal was because of religious conviction against
termination of pregnancy. Refusal of prenatal diagnosis was also related t
o a lower socio-economic background and poorer education. Only 12 per cent
of couples were properly aware of their genetic risk. Therefore, for preven
tion of genetic disorders, the emphasis in countries such as Lebanon has pr
obably to be placed on public awareness about genetic risks, the risks of c
onsanguinity, availability of services, while taking into consideration the
personal beliefs of the individuals. Copyright (C) 1999 John Wiley & Sons,
Ltd.