Enantioselective ring opening of epoxides with trimethylsilyl azide (TMSN3) in the presence of beta-cyclodextrin: an efficient route to 1,2-azido alcohols

Authors
Kamal, A Arifuddin, M Rao, MV
Citation
A. Kamal et al., Enantioselective ring opening of epoxides with trimethylsilyl azide (TMSN3) in the presence of beta-cyclodextrin: an efficient route to 1,2-azido alcohols, TETRAHEDR-A, 10(22), 1999, pp. 4261-4264
Citations number
29
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
10
Issue
22
Year of publication
1999
Pages
4261 - 4264
Database
ISI
SICI code
0957-4166(19991119)10:22<4261:EROOEW>2.0.ZU;2-D
Abstract
The ring opening of epoxides with nucleophiles such as TMSN3 and isopropyla mine takes place enantioselectively in the presence of (beta-cyclodextrin u nder extremely mild conditions and the azido alcohols and amino alcohols ar e formed as (S)-isomers. (C) 1999 Published by Elsevier Science Ltd. All ri ghts reserved.