Catalytic enantioselective borane reduction of aromatic ketones with sulfonyl (S)-prolinol

Authors
Yang, GS Hu, JB Zhao, G Ding, Y Tang, MH
Citation
Gs. Yang et al., Catalytic enantioselective borane reduction of aromatic ketones with sulfonyl (S)-prolinol, TETRAHEDR-A, 10(22), 1999, pp. 4307-4311
Citations number
15
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
10
Issue
22
Year of publication
1999
Pages
4307 - 4311
Database
ISI
SICI code
0957-4166(19991119)10:22<4307:CEBROA>2.0.ZU;2-E
Abstract
The asymmetric reduction of aromatic ketones was catalyzed by a class of re coverable and highly stable chiral sulfonamides derived from (S)-proline to yield optically active secondary alcohols in high yields and with enantiom eric excesses of up to 91%. (C) 1999 Elsevier Science Ltd. All rights reser ved.