P. Ciminiello et al., CHEMISTRY OF VERONGIDA SPONGES .8. BROMOCOMPOUNDS FROM THE MEDITERRANEAN SPONGES APLYSINA-AEROPHOBA AND APLYSINA CAVERNICOLA, Tetrahedron, 53(18), 1997, pp. 6565-6572
A detailed analysis of the secondary metabolites of Aplysina aerophoba
and Aplysina cavernicola has been performed. A number of bromotyrosin
e derivatives have been identified of which two, 14 and 15, both isola
ted from A. cavernicola, are novel compounds. Their structures have be
en assigned on the basis of spectroscopic and chemical data. The obtai
ned results indicate a remarkable difference in the secondary metaboli
sm of the two sponges, which eventually confirms the separation of the
two Mediterranean Aplysina species, in perfect agreement with Vacelet
's opinion. (C) 1997 Elsevier Science Ltd.