Secondary haematogenous joint involvement is seen in less than 1 % of patie
nts with Salmonella infections. These atypical infections are frequently en
couraged by pre-existing local or systemic disease. We present a case of a
patient with known alcohol abuse who developed a septic infection of her ri
ght hip requiring resection of the femoral head. Histologic analysis showed
signs of pre-existing osteonecrosis probably induced by alcohol intake. Ca
rtilage and bone were invaded and destructed by an aggressive granulation t
issue. Initially, a biopsy evaluated without knowledge of the positive bact
eriological result had been interpreted as indicative of a tumour. The onse
t, clinical course, diagnosis and therapy of joint involvement by Salmonell
a are discussed with regard to our case and the relevant literature. This c
ase illustrates the necessity for clinicians to share all their information
about the patient with the pathologist.