Clinical pharmacology of nervous system diseases

The approach of "partner drugs" in the treatment of bacterial meningitis is described in light of the unique pathophysiology of infection of the centr al nervous system. The current and controversial therapies of equine protoz oal myeloencephalitis are discussed. Approaches to controlling inflammation in the central nervous system are discussed, including steroidal and nonst eroidal anti-inflammatory drugs, dimethylsulfoxide (DMSO), and vitamin E. C ontrol of seizures is described with the use of phenobarbital and diazepam. Current topics in behavioral pharmacology in horses are discussed, in view of the potential for unethical use in performance horses.