NEW CHIRAL PHOSPHETANES - SYNTHESIS AND USE IN THE PALLADIUM-CATALYZED ALLYLIC ALKYLATION

Authors
MARINETTI A KRUGER V RICARD L
Citation
A. Marinetti et al., NEW CHIRAL PHOSPHETANES - SYNTHESIS AND USE IN THE PALLADIUM-CATALYZED ALLYLIC ALKYLATION, Journal of organometallic chemistry, 529(1-2), 1997, pp. 465-472
Citations number
19
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear
Journal title
Journal of organometallic chemistry → ACNP
ISSN journal
0022328X
Volume
529
Issue
1-2
Year of publication
1997
Pages
465 - 472
Database
ISI
SICI code
0022-328X(1997)529:1-2<465:NCP-SA>2.0.ZU;2-7
Abstract
The new chiral phosphetane-acetals 4a-d and 10a-d were synthesized and evaluated as coligands for the palladium-catalyzed allylic alkylation of 1,3-diphenyl-2-propenyl acetate with sodium malonate. For each set of epimeric phosphetanes, the enantiomeric excesses are highly depend ent on the relative configurations of the various chiral centers. The highest asymmetric induction was observed with phosphetane 4a. An X-ra y crystal structure of the complex (allyl)PdCl(4a) is also reported.