A study involving II commercial layer flocks was conducted to determine the
efficacy of Salmonella enteritidis bacterins (autogenous or federally lice
nsed). The criterion for evaluation of vaccine efficacy was the presence or
absence of S. enteritidis in the environment, the organs of the bird (incl
uding ovary and oviduct), and eggs. Environmental, rodent, and organ specim
ens from dead birds as well as eggs were cultured throughout the life of th
e flock All layers were obtained from pullet sources that were negative for
S. enteritidis, as determined by organ and environmental cultures. Despite
the use of S, enteritidis vaccination, 63.6% of the houses had S. enteriti
dis-positive environmental cultures and 100% of the hocks had S. enteritidi
s organ-culture-positive birds. The range of positive cultures for S. enter
itidis in the environment in vaccinated flocks was between 0 and 45.5%. Bir
ds in vaccinated flocks were organ-culture positive for S. entericidis betw
een 10% and 40% of the time. The unvaccinated portion of flocks in the same
house and the unvaccinated flock in a complex had similar results compared
with the vaccinated portion of the flocks.