Studies on production of griseofulvin

Griseofulvin is an antifungal antibiotic and is used for the treatment of m ycotic diseases of human, veterinary and plant systems. It is synthesised b y many species of Penicillium. The exploitation of fermentation process pla ys a vital role in the industrial applications. This leads to techno-econom ic feasibility of the processes. The present review mainly discusses on the production of griseofulvin in soil, in plants and by various micro-organis ms. This communication also summarises the various factors which influence the griseofulvin production and strain improvement by mutation for enhanced production.