Vascular inflammation stands at the center of innumerable physiological and
pathological processes, Dissecting the mechanisms of successful vascular i
njury and repair, investigators provide information for scientists and clin
icians. The neurologist benefits from studies across several disciplines. D
etails of the cellular functions in the infiltrates of temporal arteries im
part a basis for rational therapy. The interactions of herpes virus with ve
ssels wall remind us of the affinity of numerous infectious agents for the
vasculature. Several animal models are enabling us to explore the genetic l
inks in autoimmunity. Although clinical studies may not yet provide us with
answers for accurate diagnosis and treatment of many of our patients, data
from this year will keep our interest high. Curr Opin Neurol 12:383-388. (
C) 1999 Lippincott Williams & Wilkins.