Neural stem cells in the adult human brain

Authors
Johansson, CB Svensson, M Wallstedt, L Janson, AM Frisen, J
Citation
Cb. Johansson et al., Neural stem cells in the adult human brain, EXP CELL RE, 253(2), 1999, pp. 733-736
Citations number
17
Categorie Soggetti
Cell & Developmental Biology
Journal title
EXPERIMENTAL CELL RESEARCH
ISSN journal
00144827 → ACNP
Volume
253
Issue
2
Year of publication
1999
Pages
733 - 736
Database
ISI
SICI code
0014-4827(199912)253:2<733:NSCITA>2.0.ZU;2-G
Abstract
New neurons are continuously generated in certain regions of the adult brai n. Studies in rodents have shown that new neurons are generated from self-r enewing multipotent neural stem cells. Here we demonstrate that both the la teral ventricle wall and the hippocampus of the adult human brain harbor se lf-renewing cells capable of generating neurons, astrocytes, and oligodendr ocytes in vitro, i.e., bona fide neural stem cells. (C) 1999 Academic Press .