M. Heringlake et al., A comparison of the cuffed oropharyngeal airway (COPA) with the laryngeal mask airway (LMA) during manually controlled positive pressure ventilation, J CLIN ANES, 11(7), 1999, pp. 590-595
Study Objective: To examine the cuffed oropharyngeal airway (COPA) during p
ositive pressure ventilation (PPV) and to compare its reliability and effic
acy with the laryngeal mask airway (LMA).
Design: Prospective, randomized, controlled trial.
Setting: University Hospital.
Patients: 60 adult ASA physical status I and II patients scheduled for urol
ogic surgery.
Interventions: Patients were randomly assigned to be ventilated with a COPA
(n = 33) or a LMA (n = 27) during a standardized anesthetic procedure. Fol
lowing preoxygenation and induction with alfentanil and propofol, the respe
ctive airways were inserted. Patients were ventilated manually with the res
ervoir bag of the anesthesia respirator. Inspiratory airway pressure was li
mited to 20 cm H2O, and the target tidal volume was 7 ml/kg. Respiratory ra
te was adjusted to achieve an end-tidal pressure of carbon dioxide of 35 mm
Hg. Anesthesia was maintained with propofol, nitrous oxide in oxygen, and a
lfentanil as appropriate.
Measurements and Main Results: We evaluated ease of insertion (nominal scal
e: easy, moderate, difficult, or impossible) and recorded the number of man
euvers performed during insertion until an airtight seal of the airway was
achieved. Reliability for "hands free" ventilation-defined as ventilation w
ithout the need to further augment the position of the airway device manual
ly-was determined (nominal scale: adequate ventilation, adequate ventilatio
n with manual assistance, and inadequate ventilation leading to airway chan
ge). Ventilation and oxygenation parameters were derived from the anesthesi
a respirator and a capillary blood gas sample, respectively. The incidence
of laryngopharyngeal discomfort and the amount of salivation were assessed
by nominal scales. The COPA was easier to insert than the LMA (p < 0.001),
but more positional maneuvers (P < 0.001) were necessary with this device.
"Hands free" ventilation was achieved less often with the COPA (p < 0.02).
Ventilation and oxygenation were comparable with both devices. The COPA was
associated with less salivation (p < 0.01) and laryngopharyngeal discomfor
t (p < 0.05) than the LMA.
Conclusion: Although effective ventilation can be accomplished with both de
vices, the LMA is more reliable for "hands free" ventilation than the COPA.
The lower incidence of laryngopharyngeal discomfort and salivation with th
e COPA may be beneficial for patients at risk for developing laryngospasm.
(C) 1999 by Elsevier Science Inc.