Demystified ... The Epstein-Barr virus and its association with human cancers

Citation
Krn. Baumforth et al., Demystified ... The Epstein-Barr virus and its association with human cancers, J CL PATH-M, 52(6), 1999, pp. 307-322
Citations number
184
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology","Medical Research Diagnosis & Treatment
Journal title
JOURNAL OF CLINICAL PATHOLOGY-MOLECULAR PATHOLOGY
ISSN journal
13668714 → ACNP
Volume
52
Issue
6
Year of publication
1999
Pages
307 - 322
Database
ISI
SICI code
1366-8714(199912)52:6<307:D.TEVA>2.0.ZU;2-6
Abstract
The Epstein-Barr virus (EBV) has been linked to the development of a variet y of human malignancies, including Burkitt's lymphoma, Hodgkin's disease, n asopharyngeal carcinoma, some T cell lymphomas, post-transplant lymphoproli ferative disease, and more recently, certain cancers of the stomach and smo oth muscle. This review summarises these associations and in particular the role of the viral latent genes in the transformation process.