The 3,6-disubstituted bicycle[3.1.0]hexane unit - a conformatively highly variable system

Authors
Vilsmaier, E Roth, W Bergstrasser, U
Citation
E. Vilsmaier et al., The 3,6-disubstituted bicycle[3.1.0]hexane unit - a conformatively highly variable system, J MOL STRUC, 513(1-3), 1999, pp. 21-28
Citations number
29
Categorie Soggetti
Physical Chemistry/Chemical Physics
Journal title
JOURNAL OF MOLECULAR STRUCTURE
ISSN journal
00222860 → ACNP
Volume
513
Issue
1-3
Year of publication
1999
Pages
21 - 28
Database
ISI
SICI code
0022-2860(199912)513:1-3<21:T3BU-A>2.0.ZU;2-Z
Abstract
Conformations of 6-morpholinobicyclo[3.1.0]hexane derivatives 6a-c and 9 wi th a benzylamino, anilino, amino or ammonium moiety in 3 beta-position were studied by H-1 NMR spectroscopy. X-ray structural analysis established the presence of an unusual and almost perfect half-chair conformation for the bicyclo[3.1.0]hexane skeleton in the crystals of 6b. (C) 1999 Elsevier Scie nce B.V. All rights reserved.