The authors report the third case since 1964 of fetus-in-fetu presenting at
Red Cross Children's Hospital. A fetal liver abnormality was detected duri
ng routine antenatal ultrasound scan, and the postnatal diagnosis of an int
rahepatic, multiple fetus-in-fetu was made with abdominal ultrasound scan,
plain radiograph of the abdomen and computed tomography. The mass was remov
ed surgically by hemihepatectomy when the patient was 4 months of age. Imag
ing and the macroscopic and microscopic appearances of the abnormality conf
irmed the diagnosis and amplified it to include an adjacent teratoma. Multi
ple small subcapsular and perimass vascular hamartomas were coincidentally
discovered in the liver. Two of the 3 nodules within the amniotic-lined cav
ity of the intrahepatic mass individually comply with the accepted criteria
for fetus-in-fetu, and the third nodule has the accepted features of a ben
ign teratoma. The existence of multiple fetus-in-fetu and fetus-in-fetu com
bined with a teratoma, is recorded in the medical literature. The imaging a
s well as the macroscopic and microscopic features are illustrated. J Pedia
tr Surg 34:1861-1864. Copyright (C) 1999 by W.B. Saunders Company.