Flow-injection spectrophotometric methods for the determination of tenoxicam

Two sensitive and rapid flow-injection spectrophotometric methods are propo sed for the determination of tenoxicam (TX). In the first method, a Fe(III) -tenoxicam complex is formed in a methanolic medium and the absorbance is m easured at 540 nm, while the second method involves measurement of the abso rbance at 355 nm of a solution containing the drug in hydrochloric acid med ium. In both methods, the peak heights were proportional to tenoxicam conce ntration over the ranges 7.0-320 and 0.5-8.5 mg l(-1), respectively. The me thods have been applied to the routine determination of the drug in dosage forms. (C) 1999 Elsevier Science B.V. All rights reserved.