An area beam equalization technique has been investigated in order to gener
ate patient-specific compensating filters for digital angiography. An initi
al image was used to generate the compensating filter, which was fabricated
using a deformable compensating material, containing CeO2 and an array of
square pistons. The CeO2 attenuator thicknesses were calculated using the g
ray level information from the initial unequalized image. The array of pist
ons was pressed against a uniform thickness of attenuating material to gene
rate a filter for x-ray beam equalization. The filter was subsequently inse
rted into the x-ray beam for the final equalized radiograph. It was positio
ned close to the focal spot (magnification of 8.0) in order to minimize edg
e artifacts from the filter. The equalization of x-ray transmission across
the field exiting from the object significantly improved the image quality
by preserving local contrast throughout the image. The contrast-to-noise ra
tio (CNR) in the equalized images was increased by up to fivefold. Phantom
studies indicate that equalized images using a relatively small array of pi
stons (e.g., 8X8) produce significant improvement in image quality with neg
ligible perceptible artifacts. Animal studies showed that beam equalization
significantly improved fluoroscopic and angiographic image quality. X-ray
beam equalization produced an image with a relatively uniform scatter-glare
intensity and it reduced the scatter-glare fraction in the previously unde
rpenetrated region of the image from 0.65 to 0.50. Also, x-ray tube loading
due to the mask assembly itself was negligible. In conclusion, area beam e
qualization reduces the scatter-glare fraction and significantly improves C
NR in the previously underpenetrated region of the image. (C) 1999 American
Association of Physicists in Medicine. [S0094-2405(99)02212-9].