Jd. Port et al., Progressive multifocal leukoencephalopathy demonstrating contrast enhancement on MRI and uptake of thallium-201: a case report, NEURORADIOL, 41(12), 1999, pp. 895-898
We describe a patient with AIDS who presented with focal neurological sympt
oms, and who had contrast-enhancing brain lesions on MRI which demonstrated
increased thallium-201 uptake on SPECT. These findings were consistent wit
h lymphoma; however, brain biopsy established a diagnosis of progressive mu
ltifocal leukoencephalopathy (PML). To our knowledge, this is the first rep
orted case of PML with increased thallium-201 uptake on brain SPECT.