Progressive multifocal leukoencephalopathy demonstrating contrast enhancement on MRI and uptake of thallium-201: a case report

Citation
Jd. Port et al., Progressive multifocal leukoencephalopathy demonstrating contrast enhancement on MRI and uptake of thallium-201: a case report, NEURORADIOL, 41(12), 1999, pp. 895-898
Citations number
16
Categorie Soggetti
Neurology,"Neurosciences & Behavoir
Journal title
NEURORADIOLOGY
ISSN journal
00283940 → ACNP
Volume
41
Issue
12
Year of publication
1999
Pages
895 - 898
Database
ISI
SICI code
0028-3940(199912)41:12<895:PMLDCE>2.0.ZU;2-3
Abstract
We describe a patient with AIDS who presented with focal neurological sympt oms, and who had contrast-enhancing brain lesions on MRI which demonstrated increased thallium-201 uptake on SPECT. These findings were consistent wit h lymphoma; however, brain biopsy established a diagnosis of progressive mu ltifocal leukoencephalopathy (PML). To our knowledge, this is the first rep orted case of PML with increased thallium-201 uptake on brain SPECT.