Interaction among primary afferents, corticofugal fibers, and intrinsic ele
ments allows for sensorimotor integration at the dorsal column nuclei. The
interneurons permit the spatial localization, the recurrent collaterals syn
chronize the activity of projecting cells with overlapping receptive fields
, and the corticofugal fibers induce a central zone of activity surrounded
by a peripheral zone of inhibition.