A 30-month-old boy who has been suffering progressive proximal muscle
weakness and severe atrophy in shoulder and hip muscles from 11 months
of age had prominent perivascular inflammatory cellular infiltration
in his muscle biopsy and myopathic EMG changes. But his serum creatine
kinase (CK) levels were repeatedly found to be within normal ranges.
Oral prednisolone therapy (2 mg/kg/d) brought a complete recovery of m
uscle power and normalization of EMG and muscle biopsy findings. This
report provides an additional support that the cases of infantile poly
myositis with normal serum CK levels may respond well to steroid thera
py. (C) 1997 Elsevier Science B.V.