Decarboxylative cycloaromatization of enediyne model compounds - mechanismof the radical and ionic pathway

Authors
Wakayama, M Suzuki, I Kawakami, T Nemoto, H Shibuya, M
Citation
M. Wakayama et al., Decarboxylative cycloaromatization of enediyne model compounds - mechanismof the radical and ionic pathway, TETRAHEDR L, 41(1), 2000, pp. 95-98
Citations number
12
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
1
Year of publication
2000
Pages
95 - 98
Database
ISI
SICI code
0040-4039(20000101)41:1<95:DCOEMC>2.0.ZU;2-G
Abstract
Stable alpha-alkynylacetic acid derivatives related to cis-enediyne were sy nthesized and the rate of decarboxylative cycloaromatization of 3,5-difluor o derivative 7c was found to be much faster than that of the corresponding phenyl derivative 7a. The cycloaromatization reaction mechanisms of 7c unde r various conditions were investigated. (C) 1999 Elsevier Science Ltd. All rights reserved.