An isothermal microcalorimetric titration/perfusion vessel equipped with electrodes and spectrophotometer

A new microcalorimetric titration/perfusion vessel has been developed with special reference to needs in thermodynamic and analytical investigations o f complex processes. The vessel, which is part of a twin heat conduction mi crocalorimeter, is equipped with electrodes for determination of pH and oxy gen concentration and with light guides forming part of a died array spectr ophotometer. The dynamic properties of the instrument has been investigated . The calorimeter and its analytical sensors has been tested in titration e xperiments and in bacterial growth experiments. (C) 1999 Elsevier Science B .V. All rights reserved.