Spontaneous intestinal perforation

Background: Spontaneous intestinal perforations mainly affect preterms with in their first two weeks of life. Pathogenesis: In contrast to the findings in necrotizing enterocolitis dema rcations due to spontaneous perforations are sharply punched out of an othe rwise vital bowel section. Pathophysiologic interactions currently are poor ly understood. Arterial hypotension and vascular compromises seem to play a crucial role in the development of spontaneous intestinal perforations. Clinical aspects: Clinical characteristics are abdominal distension and gre en-blue discolouration in association with a stable general condition. Inte stinal perforations require surgical intervention in terms of primary anast omosis or barrelled stoma, for instance. Spontaneous perforations carry fav ourable prognosis with a rare chance of relapses.