This article discusses the applied science of the nursing discipline and nu
rsing issues related to Alzheimer disease. Three models are presented and i
llustrated with interdisciplinary research ideas to improve the care of per
sons who suffer from dementia of the Alzheimer type (DAT). Phases of Nursin
g Research is a five-component model to (1) identify problems, (2) conduct
the study, (3) disseminate results, (4) utilize findings that are to the ce
ntral component, (5) practical knowledge. Promoting evidence-based care for
making a recommendation against artificial feeding and providing the tools
to promote natural feeding illustrates the Interdisciplinary Collaboration
model. The Program of Research model is described by studies of late-stage
DAT, intercurrent infections, and decision making. Issues framing nursing
research are discussed and specific suggestions for research projects devel
oped from recent funding priorities of the National Institutes of Health ar
e given.