Since 1992, 42 patients at the University of Pennsylvania have been treated
for inverted papilloma (IP). Thirty-three patients were managed endoscopic
ally with or without a Caldwell Luc approach (CLA) and retrospectively anal
yzed. The CLA, which involves a gingivobuccal incision for access to the ma
xillary sinus, is distinguished from a formal Caldwell Luc procedure. These
33 patients with histologically confirmed IP were without evidence of mali
gnancy. They also did not have evidence of intracranial, orbital, or fronta
l sinus IP. Seventeen of 33 patients (17/33) were without prior treatment (
primary). Sixteen of 33 (16/33) presented from an outside institution with
recurrent IP (secondary). The recurrence rate rising this method to treat p
rimary IP was 6% (1/17), and for secondary IP was 25% (4/16). Scheduled pos
toperative endoscopic surveillance permitted early detection of recurrence
and continued endoscopic control of IP. All 33 patients were endoscopically
free of disease at the end of the study. These preliminary data ape encour
aging for the use of intranasal endoscopy with and without CLA as a means o
f managing and controlling IP in selected cases.