Nifedipine therapy 10 mg ED orally, carried out in 14 PIH pregnant subjects
on comparison with 10 normal pregnant control clearly indicates as a valua
ble therapeutic tool. Platelet serotonin uptake was markedly decreased with
reduced serotonin content after 2 weeks, with increased platelet numbers.
Clinically it controlled blood pressure, oedema and proteinuria. Calcium le
vel was statistically decreased in post-therapy group along with potassium
level with unaltered sodium level in blood. This study augmented the benefi
cial effects of nifedipine on biochemical and clinical parameters in PIH su
bjects.