Effectiveness of pneumococcal polysaccharide vaccine for preschool-age children with chronic disease

Authors
Fiore, AE Levine, OS Elliott, JA Facklam, RR Butler, JC
Citation
Ae. Fiore et al., Effectiveness of pneumococcal polysaccharide vaccine for preschool-age children with chronic disease, EM INFECT D, 5(6), 1999, pp. 828-831
Citations number
23
Categorie Soggetti
Clinical Immunolgy & Infectious Disease
Journal title
EMERGING INFECTIOUS DISEASES
ISSN journal
10806040 → ACNP
Volume
5
Issue
6
Year of publication
1999
Pages
828 - 831
Database
ISI
SICI code
1080-6040(199911/12)5:6<828:EOPPVF>2.0.ZU;2-V
Abstract
To estimate the effectiveness of pneumococcal polysaccharide vaccine, we se rotyped isolates submitted to the Pneumococcal Sentinel Surveillance System from 1984 to 1996 from 48 vaccinated and 125 unvaccinated children 2 to 5 years of age. Effectiveness against invasive disease caused by serotypes in cluded in the vaccine was 63%. Effectiveness against serotypes in the polys accharide vaccine but not in a proposed seven-valent protein conjugate vacc ine was 94%.