Botulinum toxin type A in the treatment of focal, axillary and palmar hyperhidrosis and other hyperhidrotic conditions

Focal essential hyperhidrosis is a common and often disabling disorder main ly involving the palms, axillae, face, and soles of the feet, Focal hyperhi drosis may also arise from several neurological or internal diseases. Curre nt therapeutic options include topical aluminium chloride salts, systemic a nticholinergic drugs, tap-water iontophoresis, and a number of surgical app roaches. However, none of these are entirely satisfactory, In recent studie s, injection of botulinum toxin type A (BTX-A) into the hyperhidrotic area has proved very effective in reducing or abolishing focal sweating of diffe rent aetiologies without major side effects. BTS-A therefore has the potent ial to replace more invasive therapies. Eur J Neurol 6 (suppl 4):S111-S115 (C) Lippincott Williams & Wilkins.