Human chromosomal fragile sites and malignant tumours

Authors
Nesina, IP Polishchuk, LZ
Citation
Ip. Nesina et Lz. Polishchuk, Human chromosomal fragile sites and malignant tumours, EXP ONCOL, 21(3-4), 1999, pp. 195-206
Citations number
100
Categorie Soggetti
Onconogenesis & Cancer Research
Journal title
EXPERIMENTAL ONCOLOGY
ISSN journal
02043564 → ACNP
Volume
21
Issue
3-4
Year of publication
1999
Pages
195 - 206
Database
ISI
SICI code
0204-3564(199909/12)21:3-4<195:HCFSAM>2.0.ZU;2-N
Abstract
This review presents the generalization of modern literature data about fra gile sites in human chromosomes as well as the chemical and molecular basis of their expression and structure. The association between chromosomal fra gile sites in normal cells and development of tumours is discussed.