The role of parietal fibrin deposits of blood vessels in the lung as a target organ for metastasis in C57BI/6 mice with Lewis carcinoma

Authors
Petik, AV Pyaskovskaya, ON Vinnitsky, VB
Citation
Av. Petik et al., The role of parietal fibrin deposits of blood vessels in the lung as a target organ for metastasis in C57BI/6 mice with Lewis carcinoma, EXP ONCOL, 21(3-4), 1999, pp. 239-242
Citations number
24
Categorie Soggetti
Onconogenesis & Cancer Research
Journal title
EXPERIMENTAL ONCOLOGY
ISSN journal
02043564 → ACNP
Volume
21
Issue
3-4
Year of publication
1999
Pages
239 - 242
Database
ISI
SICI code
0204-3564(199909/12)21:3-4<239:TROPFD>2.0.ZU;2-1
Abstract
The pathophysiological role of parietal fibrin deposits of blood vessel wal ls in the target organ for metastases during Lewis lung carcinoma growth in C57Bl/6 mice was investigated. The compensatory role of parietal fibrinous formations in the blood vessel's wall barrier function was shown. The pari etal fibrin deposits were found to facilitate the cell and particle attachm ent to a blood vessel wall. The role of parietal fibrin deposits in metasta sis is discussed.