We studied ten women (age: 40+/-12 years) with primary hypothyroidism. Base
line and after T4 treatment (euthyroid stage), all patients' resting ECGs w
ere recorded. After T4 treatment, QTd (P=0.036), QTad (P=0.016), JTd (P=0.0
001), JTad (P=0.005), Ted (P=0.036), QRS (P=0.046), QTcd (P=0.036), QTacd (
P=0.028), JTcd (P=0.006), JTacd (P=0.016), Tecd (P=0.036) values shortened
in patients with hypothyroidism. We found that regional inhomogeneity of ve
ntricular repolarization in patients with hypothyroidism improves after T4
treatment. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.