B. Hamm et al., Clinical utility and safety of MultiHance (R) in magnetic resonance imaging of liver cancer: Results of multicenter studies in Europe and the USA, J COMPUT AS, 23, 1999, pp. S53-S60
Citations number
26
Categorie Soggetti
Radiology ,Nuclear Medicine & Imaging","Medical Research Diagnosis & Treatment
MultiHance(R) (gadobenate dimeglumine; Gd-BOPTA, Bracco SpA, Milano, Italy)
is a novel gadolinium-based contrast agent which has recently been made co
mmercially available in Europe for magnetic resonance imaging of the liver.
It combines the properties of a conventional extracellular fluid contrast
agent with those of a liver-specific agent and has been shown in numerous c
linical trials to improve the impact of magnetic resonance imaging for both
the detection and characterization of focal liver masses. The present arti
cle briefly summarizes the safety and efficacy results of Phase I, II and I
II clinical studies carried out in almost 800 patient and non-patient volun
teers in both Europe and the USA.