MultiHance (R) in the dynamic phase of contrast enhancement: a pictorial assessment

The present article demonstrates pictorially the use of MultiHance(R) (gado benate dimeglumine, Gd-BOPTA) in dynamic magnetic resonance imaging and is aimed at ensuring that the product is not misconceived as solely a hepatobi liary agent for use in delayed, static magnetic resonance imaging for the i mproved detection of focal liver lesions. The enhancement patterns of three malignant (hepatocellular carcinoma, cholangiocarcinoma and metastasis) an d three benign (hemangioma, focal nodular hyperlasia and adenoma) lesion ty pes are demonstrated. Each was imaged during the dynamic phase of contrast enhancement immediately following the intravenous bolus administration of 0 .05 mmol/kg MultiHance(R). The article demonstrates that the enhancement pa tterns observed for these relatively common lesions are similar to those re ported in the literature after the intravenous bolus administration of conv entional, non-specific 'extracellular fluid' contrast agents, and concludes by inferring that MultiHance(R) behaves in the liver as a conventional gad olinium-based agent in the first minutes after administration.