R. Barrera et al., Flow triggering added to pressure support ventilation improves comfort andreduces work of breathing in mechanically ventilated patients, J CRIT CARE, 14(4), 1999, pp. 172-176
Purpose: The purpose of this study was to measure the effect of flow trigge
ring (FI), added to pressure support ventilation (PSV), during spontaneous
breathing in intubated patients.
Materials and Methods: A prospective observational study was conducted at a
Comprehensive Cancer Center, University Hospital. Fourteen consecutive cri
tically ill, mechanically ventilated patients on PSV with positive end-expi
ratory pressure were studied. Flow triggering was added to PSV in spontaneo
usly breathing ventilated patients,
Results: Respiratory rate (f), minute ventilation (V epsilon), patient work
of breathing (WOBp), respiratory drive (P-0.1), rapid shallow breathing in
dex (f/V-t), tidal volume (V-t) and a visual analog scare of breathing effo
rt and comfort all improved. There was a large decrease in WOBP and P-0.1 w
hen flow triggering was added to PSV (P < .001). There was a moderate decre
ase in f/V-t during the same procedure (P < .01), Twelve patients felt subj
ectively better with the intervention.
Conclusions: Flow triggering offers an excellent complement to PSV because
it improves patient comfort and reduces the magnitude of the inspiratory ef
fort as well as the delay time between inspiratory muscle contraction and g
as flow. it augments gas exchange at no metabolic cost to the patient while
reducing the work of breathing, Copyright (C) 1999 by W.B. Saunders Compan
y.