Methods for quantitation of human neutrophil proteins, a survey

Neutrophils contain a variety of proteins that endow the cell with its capa city to migrate towards and eliminate microbial pathogens, Many of these pr oteins are largely or exclusively localized to neutrophils. It is therefore of interest to quantitate these proteins in a variety of clinical settings as well as in basic research. The aim of this survey is to give an introdu ction to some of the more commonly used methods for quantitation of neutrop hil proteins and to discuss advantages and problems of the different method s and the relevance of quantitating neutrophil proteins in different biolog ical settings. (C) 1999 Elsevier Science B.V. All rights reserved.