The use of peritoneal dialysis (PD) has increased damatically over the last
two decades since the introduction of continuous ambulatory peritoneal dia
lysis (CAPD). With this has also been the improvement in outcomes. In the m
edium term (up to five years), there is no difference in patient survival w
hen CAPD is compared with hemodialysis (HD); PD technique survival is also
improving, though is somewhat less than on HD. Problem areas for PD appear
to be peritoneal membrane related changes, residual function, and peritonit
is and these would need to be impacted on to improve outcome and long-term
survival on PD. Current data would suggest that not many patients continue
on peritoneal dialysis beyond ten years. However there are developments whi
ch show promise and are likely to enhance the outcome. It is possible to ma
ximise renal replacement therapy by using peritoneal dialysis as the initia
l therapy. Arguments that favour this are discussed.